Long Term Outcome of Intravitreal Therapy with Pegaptanib Sodium in an Infant with Active Retinitis due to Postnatally Acquired Cytomegalovirus Infection
نویسندگان
چکیده
We describe the case of an infant with a retinitis due to a postnatally acquired Cytomegalovirus, successfully treated at six months of life with three cycles of intravitreal injections of pegaptanib sodium. The therapy was effective in modulating the retinal disease activity in this immunocompetent child, without any side effect observed at a long-term follow up.
منابع مشابه
Optimal management of cytomegalovirus retinitis in patients with AIDS
Cytomegalovirus (CMV) retinitis is the most common cause of vision loss in patients with acquired immunodeficiency syndrome (AIDS). CMV retinitis afflicted 25% to 42% of AIDS patients in the pre-highly active antiretroviral therapy (HAART) era, with most vision loss due to macula-involving retinitis or retinal detachment. The introduction of HAART significantly decreased the incidence and sever...
متن کاملIntravitreal Injections
Man’s invasion into the sacred inner space of the eyethe vitreous cavity began around the same time he was attempting to invade the outer space i.e. in the 1950s. Von Sallman in1944 demonstrated the efficacy of Intravitreal antibiotics in a study in which he successfully cured endophthalmitis in rabbits by Intravitreal Penicillin injection. And thus began the era of Intravitreal antibiotics. Fi...
متن کاملEliminating antibiotic prophylaxis for intravitreal injections: a consecutive series of 18,839 injections by a single surgeon.
PURPOSE By optimizing the protocol for intravitreal injections, the risk of endophthalmitis can be minimized. This study assesses the incidence of endophthalmitis and other complications after a consecutive series of intravitreal injections where all antibiotics were excluded. METHODS Injections were performed from August 1, 1997 to October 31, 2012 in outpatient examination rooms at the Reti...
متن کاملLong term visual outcome of patients with cytomegalovirus retinitis treated with highly active antiretroviral therapy.
BACKGROUND Healed cytomegalovirus (CMV) retinitis in the setting of highly active antiretroviral therapy (HAART) is complicated by inflammatory sequelae and vision loss. AIM To determine the long term visual outcome of AIDS patients with CMV retinitis who received HAART. METHODS 90 eyes of 63 consecutive AIDS patients with extramacular CMV retinitis were studied prospectively. RESULTS Imm...
متن کاملClinical Application of Drug Delivery Systems for Treating AMD
Due to transparent ocular media, it is relatively easy to observe intraocular tissues such as the vitreous and retina without invasion, and various administration approaches including intravitreal and subretinal injection, or implantation can be applicable. Since the eye-ball is a closed organ, novel therapeutic molecules such as an antisense oligonucleotide for cytomegalovirus retinitis (Fomiv...
متن کامل